My research focuses on the application of
computational tools to toxicology.
During my PhD thesis, I developed a new modelling framework and a software environment dedicated to toxicology. This work allows to represent the qualitative behaviour of a biological organism thanks to a set of rules and constraints. It is then possible to automatically check if the modelled behaviour includes known pathways of toxicity.
While detecting pathways of toxicity, building a model with this formalism also highlights gaps in the current toxicology knowledge, providing useful insights to optimize experimental strategies in exploratory toxicology.
Ph.D. funded by the Provence-Alpes-Côte d'Azur french region.
