Axel Loewe's talk : i3S Lab, June 2, 2025, 11am

Axel Loewe, head of the Computational Cardiac Modeling Group at Karlsruhe Institute of Technology, Germany, will be visiting the i3S Laboratory for three weeks starting end of May.

He will deliver a talk at i3S (Euclide-B building, conference room 007) on Monday June 2 at 11am.

You can find the details below.

 

Title : « Modeling & simulation of cardiac function : combining mechanistic models and artificial intelligence »

Abstract : We will introduce the concept of computational modeling & simulation of organ systems in the human body using the example of cardiac electrophysiology. According to the multi-scale nature of the biological system, we will start from the ion channel level and work our way up to the cellular and eventually organ scale. We will then use the concept of ensemble simulation spaces to discuss how modeling and simulation can be employed for digital twin applications enabling personalized medicine and for creating large virtual cohorts of digital chimeras enabling in silico trials and machine learning solutions. Applications include the identification of the best ablation and/or pharmacological strategy to treat atrial fibrillation and prediction of therapy success.

Short bio : Axel Loewe heads the Computational Cardiac Modeling Group at Karlsruhe Institute of Technology with a focus on cardiac electrophysiology and biomechanics. His group is committed to method development and the application of computational models to answer questions of clinical relevance at the intersection of engineering, computer science, and medicine. To develop methods and conduct simulation studies, methods of software engineering, algorithmics, numerics, signal processing, data analysis, and machine learning are used. Axel has a track record of fruitful collaboration with leading clinicians to optimize diagnosis and therapy of cardiac diseases. He studied Electrical Engineering and Information Technology in Karlsruhe and Stockholm, and obtained the PhD with distinction in Biomedical Engineering in 2013 from KIT and the Habilitation "Modeling and Simulation for Medicine" in 2021. He is a Reviewer and Guest Editor for more than 40 journals in the fields of Biomedical Engineering, Cardiology and Machine Learning. He has been awarded over 30 academic distinctions including Patient Safety Award 2018, Gips-Schüle Preis 2018, CinC Young Investigator Award 2016.