Adrien Richard
Chargé de recherche au CNRS

Laboratoire I3S - UMR 6070 du CNRS
Bâtiment Algorithme-Euclide-B - B.P. 121
2000 Route des Lucioles
06903 Sophia Antipolis - France

Tel: 04 92 94 27 51
Fax: 04 92 94 28 98
Mail: richard@unice.fr








J'organise les sémiminaires du pôle MDSC de l'I3S.


Revues internationnales

  • A. Richard, G. Rossignol, J.-P. Comet, G. Bernot, J. Guespin-Michel and A. Merieau. Boolean models of biosurfactants production in Pseudomonas fluorescens. PLoS ONE, 7(1):e24651, 2012. (web)

  • M. Mabrouki, M. Aiguier, J.-P. Comet, P. Le Gall and A. Richard. Embedding of biological regulatory networks and properties preservation. Mathematics in Computer Science , special issue, 5(3):263-288, 2011.

  • A. Richard and J.-P. Comet. Stable periodicities and negative circuits in differential systems. Journal of Mathematical Biology, 63:593-600, 2011. (pdf)

  • A. Richard. Local negative circuits and fixed points in non-expansive Boolean networks. Discrete Applied Mathematics, 159(11):1085-1093, 2011. (pdf)

  • L. Paulevé and A. Richard. Topological Fixed Points in Boolean Networks. Comptes Rendus de l'Académie des Sciences - Series I - Mathematics, 348(15-16):825 - 828, 2010. (pdf)

  • A. Richard. Negative circuits and sustained oscillations in asynchronous automata networks. Advances in Applied Mathematics, 44(4):378-392, 2010. (pdf)

  • A. Richard. Positive circuits and maximal number of fixed points in discrete dynamical systems. Discrete Applied Mathematics, 157(15):3281-3288, 2009. (pdf)

  • A. Richard. An extension of a combinatorial fixed point theorem of Shih and Dong. Advances in Applied Mathematics, 41(4):620-627, 2008. (pdf)

  • A. Richard and J.-P. Comet. Necessary conditions for multistationarity in discrete dynamical systems. Discrete Applied Mathematics, 155(18):2403-2413, 2007. (pdf)

  • (Invited review) Z. Khalis, J.-P. Comet, A. Richard and G. Bernot. The smbionet method for discovering models of gene regulatory networks. Genes, Genomes and Genomics, 3:15-22, 2009.

  • J. Ahmad, O. Roux, G. Bernot, J.-P. Comet and A. Richard. Analysing Formal Models of Genetic Regulatory Networks with Delays: Applications to Lambda phage and T-cell Activation Systems. International Journal of Bioinformatics Research and Applications, 4(3):240-262, 2008.

  • A. Richard, J.-P. Comet and G. Bernot. R. Thomas' modeling of biological regulatory networks: introduction of singular states in the qualitative dynamics. Fundamenta Informaticae, 65(4):373-392, 2005.

  • G. Bernot, J.-P. Comet, A. Richard, J. Guespin-Michel. A Fruitful Application of Formal Methods to Biological Regulatory Networks: Extending Thomas' Asynchronous Logical Approach with Temporal Logic. Journal of Theoretical Biology, 229(3):339-347, 2004.

  • J. Guespin-Michel, G. Bernot, J.-P. Comet, A. Mérieau, A. Richard, C. Hulen and B. Polack. Epigenesis and dynamic similarity in two regulatory networks in Pseudomonas aeruginosa. Acta Biotheoretica. 52 (4): 379-390, 2004.

"Proceedings" de Conférences

  • A. Richard. A fixed point theorem for Boolean networks expressed in terms of forbidden subnetworks. Proceeding of the 17th International Workshop on Cellular Automata and Discrete Complex Systems (AUTOMATA 2011), to appear in Discrete Mathematics and Theoretical Computer Science, 2011.

  • L. Paulevé and A. Richard. Static analysis of boolean networks based on interaction graphs: a survey. Proceedings of The Second International Workshop on Static Analysis and Systems Biology (SASB 2011), to appear in Electronic Notes in Theoretical Computer Science (ENTCS), 2011.

  • J. Bahi, J.-F. Couchot, C. Guyeux and A. Richard. On the link between strongly connected iteration graphs and chaotic Boolean discrete-time dynamical systems. Proceeding of the 18th International Symposium on Fundamentals of Computation Theory (FCT 2011), Lecture Note in Computer Science (LNCS), 6914, pp. 126-137, 2011.

  • M. Dénès, B. Lesage, Y. Bertot and A. Richard. Formal proof of theorems on genetic regulatory networks, Synasc'09, IEEEXplore Digital Library, 2009.

  • A. Richard. On the link between oscillations and negative circuits in discrete genetic regulatory networks, Proceedings of JOBIM 2007, pp. 613-618, 2007.

  • J. Ahmad, A. Richard, G. Bernot, J.-P. Comet and O. Roux. Delays in Biological Regulatory Networks. In IWBRA 2006 / ICCS 2006: 6th International Conference, Proceedings, Part II , volume 3992 of LNCS, 887-894, May 2006.

  • A. Richard, J.-P. Comet, G. Bernot. Graph-based Modeling of Biological Regulatory Networks : Introduction of Singular States. International workshop on Computational Methods in Systems Biology (CMSB), Paris, France, May 26-28,2004. In Proceedings CMSB 2004, LNBI 3082, pp. 58-72, 2005.

Chapitres de livre

  • A. Richard, J.-P. Comet and G. Bernot.
    Formal methods for modeling biological regulatopry networks.
    In Modern Formal Methods and Applications, Gabbar Hossam A. (Ed.), pp. 83-122, Springer, 2006.

Workhops / Conference / Ecoles... (invitations)

  • Formalisme logique, apport et défis pour la modélisation des réseaux de régulation biologique, 12-15 avril 2011, Rabat, Maroc.

  • "Dynamique des réseaux de régulation biologiques" Symposium en l'honneur de Marcelline Kaufman, 3 février, Bruxelles, 2011.

  • Thematic School on Modelling Complex Biological Systems, La Colle sur Loup, March 30 - April 3, 2009.

  • Gennetec training course: Genetic Regulatory Networks and other Complex Systems, January 19-23, Institut Henri Poincarée, Paris, 2009.

  • Discrete models of biological networks : from structure to dynamics, CIRM (Marseille Luminy) 3 - 7 novembre 2008.

  • International Bioinformatics Software School IBSS'2008, 3th - 8th November, Tangier, Morocco.

  • "The logic of gene regulatory networks" "La logique des réseaux de régulation génétique" In the honor of Prof. René Thomas on the occasion of his 80th birthday. Brussels, 30-31 May 2008.(slides (pdf))

  • A. Richard, Jean-Paul Comet and Gilles Bernot. R. Thomas' logical method . Modelling Complex Biological Systems in the Context of Genomics, Villeneuve d'Ascq, April 7-11, 2008. (pdf)

  • On the link between oscillations and negative circuits in discrete genetic regulatory networks. JOBIM, 10-12 juillet, Marseille, France, 2007.

  • Elisabeth Remy and Adrien Richard. Discrete modeling and dynamical analysis of genetic regulatory networks. Behavioral Economics in the Light of Mathematics, Psychology, Cognition and Bio Informatics,Aix en Provence, November 10--11, 2006.

  • Necessary conditions for multi-attractivity in discrete dynamical systems. Workshop "Dynamics and structure of biological networks" (Geocal06), Marseille-Luminy, February 14-17, 2006.

  • A. Iartseva, D. Mestivier, P.Y. Boëlle, A. Richard, G. Hutzler. Views on the choice of simulation tools, compared in the context of the same model: the bacteriophage Lambda. Complexity Advanced Course: From functional genomics to molecular networks and back , Evry, France, May 30th to June 4th, 2005.

  • D. Mestivier, A. Richard, G. Hutsler et A. Spicher. Ateliers de démonstration et de comparaison d'outils de modélisation autour de modèles biologiques communs. Modélisation de systèmes biologiques complexes dans le contexte de la génomique , Bordeaux, du 3 au 7 avril 2006.

  • A. Iartseva, D. Mestivier, P.Y. Boëlle, A. Richard, G. Hutzler. Ateliers de démonstration et de comparaison d'outils de modélisation autour de modèles biologiques communs. Modélisation de systèmes biologiques complexes dans le contexte de la génomique Montpellier, 4 - 8 avril, 2005.

  • Modélisation Qualitative de la Dynamique du Réseau de Régulation Génétique Controlant L'Immunité du Bactériophage Lambda. Modélisation et simulation de processus biologiques dans le contexte génomique, Evry, 29 mars - 2 avril, 2004.